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Epidermal growth factor receptor

Summary

UniProt ID

Q01279

Gene Symbol

Egfr

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003854

GlyConnect

2297

GlyGen

Q01279

PubChem

Q01279

Annotation

Keyword

ATP-binding
Cell membrane
Developmental protein
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Hydroxylation
Isopeptide bond
Methylation
Nucleus
Palmitate
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **51 - 60** of 80 in total

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GO Term
epithelial cell proliferation
positive regulation of epithelial cell proliferation
morphogenesis of an epithelial fold
cell-cell adhesion
cerebral cortex cell migration
neurogenesis
positive regulation of cell growth
lung development
positive regulation of superoxide anion generation
cellular response to reactive oxygen species

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GO Term
basolateral plasma membrane
apical plasma membrane
early endosome membrane
membrane raft
endosome
endoplasmic reticulum membrane
basal plasma membrane
cell surface
ruffle membrane
perinuclear region of cytoplasm

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GO Term
chromatin binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane signaling receptor activity
signaling receptor binding
kinase activity
protein-containing complex binding
protein kinase binding
transmembrane receptor protein tyrosine kinase activator activity
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MRPSGTARTTLLVLLTALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHRCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGIMGENNTLVWKYADANNVCHLCHANCTYGCAGPGLQGCEVWPSGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSATSNNSTVACINRNGSCRVKEDAFLQRYSSDPTGAVTEDNIDDAFLPVPEYVNQSVPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVGNPEYLNTAQPTCLSSGFNSPALWIQKGSHQMSLDNPDYQQDFFPKETKPNGIFKGPTAENAEYLRVAPPSSEFIGA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
128		17406563 22823882 23002422
175		17406563 22823882
196		22823882
234		22823882 23002422
352		17406563 22823882
444		22823882 23002422
528		17406563 22823882 23002422
568		17406563 22823882 23002422
603		17406563 22823882 23002422
615		23002422