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Metabotropic glutamate receptor 5

Summary

UniProt ID

Q3UVX5

Gene Symbol

Grm5
Gprc1e
Mglur5

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0004966

GlyConnect

2510

GlyGen

Q3UVX5

PubChem

Q3UVX5

The O-GlcNAc Database

Q3UVX5

O-GlcNAcAtlas

Q3UVX5

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **11 - 19** of 19 in total

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GO Term
positive regulation of long-term neuronal synaptic plasticity
regulation of DNA-templated transcription
desensitization of G protein-coupled receptor signaling pathway
protein kinase C-activating G protein-coupled receptor signaling pathway
learning
positive regulation of MAPK cascade
calcium-mediated signaling using intracellular calcium source
trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
cellular response to amyloid-beta

Displaying entries **1 - 10** of 11 in total

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GO Term
cytoplasm
plasma membrane
neuron projection
postsynaptic membrane
dendrite
astrocyte projection
glutamatergic synapse
dendritic shaft
dendritic spine
Schaffer collateral - CA1 synapse

Displaying **all 10** entries
GO Term
G protein-coupled receptor activity
glutamate receptor activity
protein tyrosine kinase activator activity
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
A2A adenosine receptor binding
protein tyrosine kinase binding
identical protein binding
PLC activating G protein-coupled glutamate receptor activity
adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Annotation information from UniProt.

Sequence

MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLRSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQHRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSTRGQHLWQRLSVHINKKENPNQTAVIKPFPKSTESRGQGAGAGGGSGPGAAGAGSAGCTATGGPEPPDAGPKALYDVAEAEERFPAAARPRSPSPISTLSHLAGSAGRTDDDAPSLHSETAARSSSSQGSLMEQISSVVTRFTANITELNSMMLSTAAAPGPPGTPICSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPATGPSPAQETPAGAEAAPGKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTLIIRDYTQSSSSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
377		17406563 22823882
381		17406563 22823882

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Class C/3 (Metabotropic glutamate/pheromone receptors)	Mus musculus
G alpha (q) signalling events	Mus musculus
Neurexins and neuroligins	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements