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Toll-like receptor 2

Summary

UniProt ID

Q9QUN7

Gene Symbol

Tlr2

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007648
GlyGen: Q9QUN7
PubChem: Q9QUN7
RaftProt: Q9QUN7

Annotation

Keyword

3D-structure
Cell membrane
Cytoplasmic vesicle
Direct protein sequencing
Disulfide bond
Glycoprotein
Inflammatory response
Innate immunity
Isopeptide bond
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **21 - 30** of 57 in total

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GO Term
positive regulation of nitric oxide biosynthetic process
positive regulation of oligodendrocyte differentiation
negative regulation of phagocytosis
positive regulation of nitric-oxide synthase biosynthetic process
negative regulation of synapse assembly
positive regulation of macrophage cytokine production
response to fatty acid
positive regulation of intracellular signal transduction
positive regulation of neutrophil migration
neutrophil migration

Displaying **all 10** entries
GO Term
Golgi apparatus
plasma membrane
cell projection
cell body
phagocytic vesicle membrane
membrane raft
external side of plasma membrane
cell surface
Toll-like receptor 1-Toll-like receptor 2 protein complex
Toll-like receptor 2-Toll-like receptor 6 protein complex

Displaying **all 10** entries
GO Term
transmembrane signaling receptor activity
signaling receptor activity
pattern recognition receptor activity
protein-containing complex binding
NAD+ nucleotidase, cyclic ADP-ribose generating
amyloid-beta binding
triacyl lipopeptide binding
diacyl lipopeptide binding
lipopeptide binding
lipoteichoic acid binding

Annotation information from UniProt.

Sequence

MLRALWLFWILVAITVLFSKRCSAQESLSCDASGVCDGRSRSFTSIPSGLTAAMKSLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSLEHLDLSDNHLSSLSSSWFGPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDFAGLTSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLELRDTNLARFQFSPLPVDEVSSPMKKLAFRGSVLTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVTIRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQELYISRNKLKTLPDASLFPVLLVMKIRENAVSTFSKDQLGSFPKLETLEAGDNHFVCSCELLSFTMETPALAQILVDWPDSYLCDSPPRLHGHRLQDARPSVLECHQAALVSGVCCALLLLILLVGALCHHFHGLWYLRMMWAWLQAKRKPKKAPCRDVCYDAFVSYSEQDSHWVENLMVQQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILVLLEPIERKAIPQRFCKLRKIMNTKTYLEWPLDEGQQEVFWVNLRTAIKS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
442		17406563 22823882

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Beta defensins	Mus musculus
Neutrophil degranulation	Mus musculus
Regulation of TLR by endogenous ligand	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements