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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Disintegrin and metalloproteinase domain-containing protein 17
Summary
- UniProt ID
- Q9Z0F8
- Gene Symbol
-
- Adam17
- Tace
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0007821
- PubChem
- Q9Z0F8
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphoprotein
- Reference proteome
- SH3-binding
- Secreted
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of ERK1 and ERK2 cascade |
| negative regulation of cold-induced thermogenesis |
| GO Term |
|---|
| extracellular region |
| cytoplasm |
| plasma membrane |
| membrane |
| apical part of cell |
| cell surface |
Sequence
MRRRLLILTTLVPFVLAPRPPEEAGSGSHPRLEKLDSLLSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMDSASVRIIKPFPAPQTPGRLQALQPAAMMPPVPAAPKLDHQRMDTIQEDPSTDSHADDDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 539 |
|
|
||
| 606 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulated proteolysis of p75NTR | Mus musculus |
| TNF signaling | Mus musculus |
