Low affinity immunoglobulin gamma Fc region receptor III-A

Summary
UniProt ID
E2RP87
Gene Symbol
  • FCGR3A
Organism
Canis lupus familiaris (dog)
External Links
Annotation
Keyword
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • IgG-binding protein
  • Immunoglobulin domain
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying 1 entry
GO Term
cell surface receptor signaling pathway
Displaying 1 entry
GO Term
plasma membrane
Displaying all 2 entries
GO Term
transmembrane signaling receptor activity
IgG binding
Sequence
MWQLVSSTALLLLVSAGTQAADVPKAVVVLEPKWNRVLTMDSVTLKCQGDHLLRDNYTWLHNGRPISNQISTYIIKNASIKNSGEYRCQTDQSKLSDPVQLEVHTGWLLLQVPRLVFQEGELIQLKCHSWKNTPVRNVQYFQNGRGKKFFYNNSEYHIPAATSEHNGSYFCRGIIGKKNESSEAVNIIIQGSSLPSTSLLLSHWPQIPFSLVMALLFAVDTGLYFAVQRDLRSSMGNLKNSKVIWSQGS
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
56 N-linked (GlcNAc...) asparagine
77 N-linked (GlcNAc...) asparagine
152 N-linked (GlcNAc...) asparagine
166 N-linked (GlcNAc...) asparagine
179 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
FCGR activation Canis familiaris
Neutrophil degranulation Canis familiaris
Post-translational modification: synthesis of GPI-anchored proteins Canis familiaris
Regulation of actin dynamics for phagocytic cup formation Canis familiaris
Role of phospholipids in phagocytosis Canis familiaris

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024