GlyCosmos Portal

Submissions

5,6-dihydroxyindole-2-carboxylic acid oxidase

Summary

UniProt ID

P07147

Gene Symbol

Tyrp1
Tyrp-1

Organism

Mus musculus (house mouse)

External Links

PubChem: P07147

Annotation

Keyword

3D-structure
Albinism
Copper
Disease variant
Disulfide bond
Glycoprotein
Melanin biosynthesis
Metal-binding
Monooxygenase
Reference proteome
Signal
Transmembrane helix
Zinc

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
melanin metabolic process
melanin biosynthetic process from tyrosine
melanocyte differentiation
melanosome organization
pigmentation
positive regulation of melanin biosynthetic process
acetoacetic acid metabolic process

Displaying **all 4** entries
GO Term
endosome membrane
melanosome
melanosome membrane
clathrin-coated endocytic vesicle membrane

Displaying **all 4** entries
GO Term
metal ion binding
identical protein binding
protein homodimerization activity
tyrosinase activity

Annotation information from UniProt.

Sequence

MKSYNVLPLAYISLFLMLFYQVWAQFPRECANIEALRRGVCCPDLLPSSGPGTDPCGSSSGRGRCVAVIADSRPHSRHYPHDGKDDREAWPLRFFNRTCQCNDNFSGHNCGTCRPGWRGAACNQKILTVRRNLLDLSPEEKSHFVRALDMAKRTTHPQFVIATRRLEDILGPDGNTPQFENISVYNYFVWTHYYSVKKTFLGTGQESFGDVDFSHEGPAFLTWHRYHLLQLERDMQEMLQEPSFSLPYWNFATGKNVCDVCTDDLMGSRSNFDSTLISPNSVFSQWRVVCESLEEYDTLGTLCNSTEGGPIRRNPAGNVGRPAVQRLPEPQDVTQCLEVRVFDTPPFYSNSTDSFRNTVEGYSAPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYAYEVQWPGQEFTVSEIITIAVVAALLLVAAIFGVASCLIRSRSTKNEANQPLLTDHYQRYAEDYEELPNPNHSMV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
96	N-linked (GlcNAc...) asparagine	UniProt
104	N-linked (GlcNAc...) asparagine	UniProt
181	N-linked (GlcNAc...) asparagine	UniProt
304	N-linked (GlcNAc...) asparagine	UniProt
350	N-linked (GlcNAc...) asparagine	UniProt
385	N-linked (GlcNAc...) asparagine	UniProt