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Tyrosine-protein kinase Fgr

Summary

UniProt ID

P09769

Gene Symbol

FGR
SRC2

Organism

Homo sapiens (human)

External Links

GlyGen: P09769
PubChem: P09769
The Human Metabolome Database: HMDBP01391
The O-GlcNAc Database: P09769
RaftProt: P09769

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Cell projection
Cytoskeleton
Innate immunity
Mitochondrion inner membrane
Myristate
Palmitate
Phosphoprotein
Proto-oncogene
Reference proteome
SH2 domain
SH3 domain
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 24 in total

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GO Term
positive regulation of cytokine production
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
peptidyl-tyrosine phosphorylation
cell differentiation
positive regulation of cell migration
innate immune response
regulation of innate immune response
regulation of protein kinase activity
bone mineralization

Displaying entries **1 - 10** of 11 in total

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GO Term
extracellular region
plasma membrane
actin cytoskeleton
extracellular exosome
aggresome
secretory granule lumen
mitochondrial inner membrane
cytosol
mitochondrial intermembrane space
extrinsic component of cytoplasmic side of plasma membrane

Displaying **all 8** entries
GO Term
protein tyrosine kinase activity
signaling receptor binding
protein kinase binding
phosphotyrosine residue binding
non-membrane spanning protein tyrosine kinase activity
ATP binding
immunoglobulin receptor binding
Fc-gamma receptor I complex binding

Annotation information from UniProt.

Sequence

MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
181			G49108TO	GlyGen The O-GlcNAc Database
183			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
FCGR activation	Homo sapiens
FCGR3A-mediated IL10 synthesis	Homo sapiens
FCGR3A-mediated phagocytosis	Homo sapiens
Neutrophil degranulation	Homo sapiens
Platelet sensitization by LDL	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements