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Apolipoprotein E

Summary

UniProt ID

P0DN41

Gene Symbol

APOE

Organism

Bos grunniens (domestic yak)

External Links

Annotation

Keyword

Chylomicron
Endosome
Extracellular matrix
Glycoprotein
HDL
Heparin-binding
Lipid transport
Lipid-binding
Oxidation
Phosphoprotein
Reference proteome
Repeat
Signal
VLDL

Gene Ontology (GO)

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GO Term
lipoprotein biosynthetic process
lipoprotein catabolic process
regulation of protein-containing complex assembly
negative regulation of neuron apoptotic process
negative regulation of blood vessel endothelial cell migration
positive regulation of nitric oxide biosynthetic process
positive regulation of endocytosis
positive regulation of lipid biosynthetic process
negative regulation of smooth muscle cell proliferation
artery morphogenesis

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GO Term
extracellular exosome
glutamatergic synapse
endoplasmic reticulum
synaptic cleft
chylomicron remnant
very-low-density lipoprotein particle
low-density lipoprotein particle
intermediate-density lipoprotein particle
high-density lipoprotein particle
extracellular space

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GO Term
heparin binding
enzyme binding
very-low-density lipoprotein particle receptor binding
lipoprotein particle binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
cholesterol transfer activity
identical protein binding
protein homodimerization activity
heparan sulfate proteoglycan binding

Annotation information from UniProt.

Sequence

MKVLWVAVVVALLAGCQADMEGELGPEEPLTTQQPRGKDSQPWEQALGRFWDYLRWVQTLSDQVQEELLNTQVIQELTALMEETMKEVKAYKEELEGQLGPMAQETQARVSKELQAAQARLGSDMEDLRNRLAQYRSEVQAMLGQSTEELRARMASHLRKLRKRLLRDADDLKKRLAVYQAGASEGAERSLSAVRERFGPLVEQGQSRAATLSTLAGQPLLERAEAWRQKLHGRLEEVGVRAQDRLDKIRQQLEEVHAKVEEQGNQMRLQAEAFQARLRSWFEPLVEDMQRQWAGLVEKVQLALRPSPTSPPSENH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites