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Heat shock protein HSP 90-beta

Summary

UniProt ID

P11499

Gene Symbol

Hsp90ab1
Hsp84
Hsp84-1
Hspc3
Hspcb

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003350
GlyGen: P11499
PubChem: P11499
The Human Metabolome Database: HMDBP14552
The O-GlcNAc Database: P11499
RaftProt: P11499
O-GlcNAcAtlas: P11499

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Cell membrane
Chaperone
Cytoplasm
Direct protein sequencing
Glycoprotein
Methylation
Nucleus
Phosphoprotein
Reference proteome
S-nitrosylation
Secreted
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of transforming growth factor beta receptor signaling pathway
regulation of protein ubiquitination
cellular response to heat
positive regulation of cyclin-dependent protein kinase activity
positive regulation of cell size
protein folding
telomere maintenance via telomerase
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein import into nucleus
chaperone-mediated protein complex assembly

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GO Term
extracellular region
nucleus
cytoplasm
lysosomal membrane
plasma membrane
protein-containing complex
melanosome
neuronal cell body
ooplasm
HSP90-CDC37 chaperone complex

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GO Term
nitric-oxide synthase regulator activity
TPR domain binding
heat shock protein binding
ubiquitin protein ligase binding
protein homodimerization activity
ATP-dependent protein binding
protein folding chaperone
protein dimerization activity
tau protein binding
unfolded protein binding

Annotation information from UniProt.

Sequence

MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRMEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
46				GlycoProtDB
283			G80920RR	GlyGen
389			G80920RR	GlyGen
434	O-linked (GlcNAc) serine	22556278	G49108TO	UniProt GlyGen The O-GlcNAc Database
452	O-linked (GlcNAc) serine	22556278	G49108TO	UniProt GlyGen The O-GlcNAc Database
462			G49108TO	GlyGen The O-GlcNAc Database
614			G02815KT	GlyGen
			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Aryl hydrocarbon receptor signalling	Mus musculus
Attenuation phase	Mus musculus
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Mus musculus
ESR-mediated signaling	Mus musculus
Estrogen-dependent gene expression	Mus musculus
HSF1 activation	Mus musculus
HSF1-dependent transactivation	Mus musculus
HSP90 chaperone cycle for SHRs	Mus musculus
Neutrophil degranulation	Mus musculus
RHOBTB2 GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Annotation

International Collaboration

Acknowledgements