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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
AP-2 complex subunit alpha-1
Summary
- UniProt ID
- P17426
- Gene Symbol
-
- Ap2a1
- Adtaa
- Clapa1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Coated pit
- Endocytosis
- Phosphoprotein
- Protein transport
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| postsynaptic endocytic zone |
| AP-2 adaptor complex |
| glutamatergic synapse |
| membrane coat |
| filopodium tip |
| basolateral plasma membrane |
| apical plasma membrane |
| clathrin-coated vesicle |
| secretory granule |
| protein-containing complex |
| GO Term |
|---|
| protein kinase binding |
| protein-containing complex binding |
| low-density lipoprotein particle receptor binding |
| clathrin adaptor activity |
Sequence
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAASALDDSRRDTSSNDINGGVEPTPSTVSTPSPSADLLGLRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFLPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGTAQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELLAQQF
Glycosylation Sites
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Mus musculus |
| Clathrin-mediated endocytosis | Mus musculus |
| LDL clearance | Mus musculus |
| MHC class II antigen presentation | Mus musculus |
| Recycling pathway of L1 | Mus musculus |
| Retrograde neurotrophin signalling | Mus musculus |
| Trafficking of GluR2-containing AMPA receptors | Mus musculus |
| VLDLR internalisation and degradation | Mus musculus |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | Mus musculus |
| WNT5A-dependent internalization of FZD4 | Mus musculus |
