T-cell surface glycoprotein CD4

Summary
UniProt ID
P33705
Gene Symbol
  • CD4
Organism
Canis lupus familiaris (dog)
External Links
PubChem
P33705
Annotation
Keyword
  • Adaptive immunity
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Palmitate
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Sequence
MNQEAAFRHLLLMLQLVMLPAVTPVREVVLGKAGDAVELPCQTSQKKNIHFNWRDSSMVQILGNQGSFWTVGSSRLKHRVESKKNLWDQGSFPLVIKDLEVADSGIYFCDTDKRQEVELLVFNLTAKWDSGSSSGSSNIRLLQGQQLTLTLENPSGSSPSVQWKGPGNKSKHGGQNLSLSWPELQDGGTWTCIISQSQKTVEFNINVLVLAFQKVSNTFYAREGDQVEFSFPLSFEDENLVGELRWQAQGASSSLLWISFTLENRKLSMKEAHAPLKLQMKESLPLRFTLPQVLSRYAGSGILTLNLAKGTLYQEVNLVVMRANSSQNNLTCEVLGPTSPELTLSLNLKEQAAKVSKQQKLVWVVDPEGGTWQCLLSDKDKVLLASSLNVSSPVVIKSWPKFLAITLGGILGLLLLIGLCVFCCVKCWRRRRQAERMSQIKRLLSEKKTCQCSHRIQKTCSLI
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
123 N-linked (GlcNAc...) asparagine
168 N-linked (GlcNAc...) asparagine
176 N-linked (GlcNAc...) asparagine
324 N-linked (GlcNAc...) asparagine
329 N-linked (GlcNAc...) asparagine
389 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 8 entries
Pathway Name Organism
Cargo recognition for clathrin-mediated endocytosis Canis familiaris
Clathrin-mediated endocytosis Canis familiaris
Downstream TCR signaling Canis familiaris
Generation of second messenger molecules Canis familiaris
Other interleukin signaling Canis familiaris
PD-1 signaling Canis familiaris
Phosphorylation of CD3 and TCR zeta chains Canis familiaris
Translocation of ZAP-70 to Immunological synapse Canis familiaris

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024