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Dual specificity mitogen-activated protein kinase kinase 3

Summary

UniProt ID

P46734

Gene Symbol

MAP2K3
MEK3
MKK3
PRKMK3
SKK2

Organism

Homo sapiens (human)

External Links

GlyGen: P46734
PubChem: P46734
The Human Metabolome Database: HMDBP02743
The O-GlcNAc Database: P46734

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Disease variant
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

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GO Term
regulation of cytokine production
inflammatory response
signal transduction
heart development
phosphorylation
positive regulation of blood vessel endothelial cell migration
positive regulation of protein kinase activity
positive regulation of nitric-oxide synthase biosynthetic process
cardiac muscle contraction
stress-activated protein kinase signaling cascade

Displaying **all 4** entries
GO Term
cytoplasm
membrane
cytosol
nucleoplasm

Displaying **all 6** entries
GO Term
protein serine/threonine kinase activity
protein tyrosine kinase activity
protein kinase binding
MAP kinase kinase activity
ATP binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MESPASSQPASMPQSKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites