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Xanthine dehydrogenase/oxidase

Summary

UniProt ID

Q00519

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q00519
PubChem: Q00519
The O-GlcNAc Database: Q00519

Annotation

Keyword

2Fe-2S
Cytoplasm
Direct protein sequencing
Disulfide bond
FAD
Molybdenum
NAD
Oxidoreductase
Peroxisome
Reference proteome
Secreted

Gene Ontology (GO)

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GO Term
negative regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
lactation
negative regulation of gene expression
regulation of epithelial cell differentiation
negative regulation of endothelial cell differentiation
positive regulation of reactive oxygen species metabolic process
negative regulation of vasculogenesis
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
iron-sulfur cluster assembly

Displaying **all 4** entries
GO Term
extracellular space
peroxisome
cytosol
sarcoplasmic reticulum

Displaying entries **1 - 10** of 14 in total

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GO Term
iron ion binding
flavin adenine dinucleotide binding
2 iron, 2 sulfur cluster binding
molybdenum ion binding
nitrite reductase (NO-forming) activity
identical protein binding
protein homodimerization activity
molybdopterin cofactor binding
oxidoreductase activity
xanthine dehydrogenase activity

Annotation information from UniProt.

Sequence

MTRTTVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTKKLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCMSQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQVSTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGAACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEELLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDPTFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATGTPENCKSWSVRI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites