GlyCosmos Portal

Submissions

Tumor necrosis factor receptor type 1-associated DEATH domain protein

Summary

UniProt ID

Q15628

Gene Symbol

TRADD

Organism

Homo sapiens (human)

External Links

GlyGen: Q15628
PubChem: Q15628
The O-GlcNAc Database: Q15628

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Cytoskeleton
Glycoprotein
Nucleus
Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 10** of 13 in total

1

2

Next ›

Last »
GO Term
apoptotic process
signal transduction
positive regulation of cell migration
positive regulation of inflammatory response
positive regulation of apoptotic process
positive regulation of hair follicle development
canonical NF-kappaB signal transduction
positive regulation of canonical NF-kappaB signal transduction
positive regulation of NF-kappaB transcription factor activity
extrinsic apoptotic signaling pathway

Displaying **all 9** entries
GO Term
death-inducing signaling complex
cytosol
tumor necrosis factor receptor superfamily complex
cytoplasmic side of plasma membrane
nucleus
cytoplasm
cytoskeleton
plasma membrane
receptor complex

Displaying **all 7** entries
GO Term
protein-containing complex binding
kinase binding
molecular adaptor activity
death domain binding
identical protein binding
transmembrane receptor protein tyrosine kinase adaptor activity
tumor necrosis factor receptor binding

Annotation information from UniProt.

Sequence

MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
235	(Microbial infection) N-beta-linked (GlcNAc) arginine	23955153 30979585 32766249		UniProt
245	(Microbial infection) N-beta-linked (GlcNAc) arginine	32766249		UniProt
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
Pathway Name	Organism
CASP8 activity is inhibited	Homo sapiens
Defective RIPK1-mediated regulated necrosis	Homo sapiens
Dimerization of procaspase-8	Homo sapiens
Ligand-dependent caspase activation	Homo sapiens
RIPK1-mediated regulated necrosis	Homo sapiens
Regulation by c-FLIP	Homo sapiens
Regulation of TNFR1 signaling	Homo sapiens
Regulation of necroptotic cell death	Homo sapiens
TNF signaling	Homo sapiens
TNFR1-induced NF-kappa-B signaling pathway	Homo sapiens