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Paired amphipathic helix protein Sin3a

Summary

UniProt ID

Q60520

Gene Symbol

Kiaa4126
Sin3a

Gene ID

20466

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60520
PubChem: Q60520
The O-GlcNAc Database: Q60520
O-GlcNAcAtlas: Q60520
Re-Glyco: Q60520

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Biological rhythms
Coiled coil
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
kinetochore
transcription regulator complex
transcription repressor complex
Sin3-type complex
nucleus
nucleolus
nucleoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 28 in total

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GO Term
type I interferon-mediated signaling pathway
negative regulation of stem cell population maintenance
positive regulation of stem cell population maintenance
response to methylglyoxal
cellular response to tert-butyl hydroperoxide
positive regulation of defense response to virus by host
cellular response to dopamine
negative regulation of transcription by RNA polymerase II
activation of innate immune response
DNA replication

Displaying **all 7** entries
GO Term
chromatin binding
DNA binding
transcription corepressor activity
RNA binding
protein-containing complex binding
RNA polymerase II-specific DNA-binding transcription factor binding
transcription regulator inhibitor activity

Annotation information from UniProt.

Sequence

MKRRLDDQESPVYAAQQRRIPGSTEAFSHQHRVLAPAPPVYEAVSETMQSATGIQYSVAPNYQVSAVPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSSQSAPTPAQPAPQPTAAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRHSGTGATPPVKKKPKLMSLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLESFPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLNSQTSRSLLESAYQRKAEQLMSDENCFKLMFIQSQGQVQLTVELLDTEEENSDDPVEAERWSDYVERYMSSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTMENVESLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKYGTVFKAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	GlyTouCan ID	Source
28	G49108TO	The O-GlcNAc Database
237		GlyGen
246		GlyGen
251	G49108TO	GlyGen The O-GlcNAc Database
266	G49108TO	The O-GlcNAc Database
295	G49108TO	The O-GlcNAc Database
436		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Cytoprotection by HMOX1	Mus musculus
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Mus musculus
Regulation of MECP2 expression and activity	Mus musculus
Regulation of MITF-M-dependent genes involved in apoptosis	Mus musculus
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	Mus musculus
Regulation of lipid metabolism by PPARalpha	Mus musculus
SUMOylation of transcription cofactors	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements