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ATP-dependent RNA helicase DDX3X

Summary

UniProt ID

Q62167

Gene Symbol

Ddx3x
D1Pas1-rs2
Ddx3
Dead3
Erh

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q62167
PubChem: Q62167
The O-GlcNAc Database: Q62167
RaftProt: Q62167

Annotation

Keyword

Acetylation
Apoptosis
Cell membrane
Cell projection
Chromosome partition
DNA-binding
Direct protein sequencing
Helicase
Inflammasome
Inflammatory response
Innate immunity
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Ribosome biogenesis
Transcription regulation
Translation regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 43 in total

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GO Term
positive regulation of NLRP3 inflammasome complex assembly
positive regulation of protein K63-linked ubiquitination
positive regulation of protein acetylation
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway
positive regulation of protein serine/threonine kinase activity
cellular response to arsenic-containing substance
primary miRNA processing
positive regulation of protein autophosphorylation
positive regulation of transcription by RNA polymerase II

Displaying **all 9** entries
GO Term
nucleus
cytoplasm
plasma membrane
cell leading edge
lamellipodium
P granule
centrosome
cytoplasmic stress granule
NLRP3 inflammasome complex

Displaying entries **1 - 10** of 17 in total

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GO Term
DNA binding
RNA binding
transcription factor binding
protein serine/threonine kinase activator activity
gamma-tubulin binding
ribosomal small subunit binding
mRNA 5'-UTR binding
ATP hydrolysis activity
DNA helicase activity
RNA helicase activity

Annotation information from UniProt.

Sequence

MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRGDSRGKSSFFGDRGSGSRGRFDDRGRGDYDGIGGRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAFEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGGSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites