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Methylosome protein WDR77

Summary

UniProt ID

Q99J09

Gene Symbol

Wdr77
Mep50

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q99J09
PubChem: Q99J09
The O-GlcNAc Database: Q99J09
O-GlcNAcAtlas: Q99J09

Annotation

Keyword

Cytoplasm
Nucleus
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation pathway
WD repeat

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
positive regulation of mRNA splicing, via spliceosome
oocyte axis specification
positive regulation of cell population proliferation
negative regulation of cell population proliferation
epithelial cell proliferation involved in prostate gland development
negative regulation of epithelial cell proliferation involved in prostate gland development
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
regulation of transcription by RNA polymerase II
protein polyubiquitination
spliceosomal snRNP assembly

Displaying **all 7** entries
GO Term
Cul4B-RING E3 ubiquitin ligase complex
cytosol
nucleoplasm
nucleus
cytoplasm
Golgi apparatus
methylosome

Displaying **all 3** entries
GO Term
ubiquitin ligase-substrate adaptor activity
nuclear receptor coactivator activity
methyl-CpG binding

Annotation information from UniProt.

Sequence

MRKDTPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGSLLLGVSSLSGRCWVGSLWFFKDPSAAPNEGFCSAGVQTEAGVADLTWVGDKGILVASDSGAVELWELDENETLIVSKFCKYEHDDIVSTVTVLSSGTQAVSGSKDCCIKIWDLAQQVSLNSYRAHAGQVTCVAASPHKDSVFLSCSEDSRILLWDTRCPKPASQMACNASGYLPTALAWHPQQSEVFVFGDENGSVSLVDTKNASCTLSSAVHSQGVTRLVFSPHSVPLLTSLSEDCSLAVLDSSLSEVFRSRAHRDFVRDATWSPLNHSLLTTVGWDHQVIHHVVPLEPLPNPGPDSVVE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites