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Angiotensin-converting enzyme 2

Summary

UniProt ID

Q9BYF1

Gene Symbol

ACE2

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0012545

GlyConnect

1012

GlyGen

Q9BYF1

PubChem

Q9BYF1

The Human Metabolome Database

HMDBP08177

The O-GlcNAc Database

Q9BYF1

RaftProt

Q9BYF1

Annotation

Keyword

3D-structure
Alternative splicing
Carboxypeptidase
Cell membrane
Cell projection
Chloride
Cytoplasm
Direct protein sequencing
Disulfide bond
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Isopeptide bond
Metal-binding
Metalloprotease
Phosphoprotein
Reference proteome
Secreted
Signal
Transmembrane helix
Ubl conjugation
Zinc

Gene Ontology (GO)

Displaying entries **1 - 10** of 26 in total

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GO Term
viral life cycle
receptor-mediated endocytosis of virus by host cell
receptor-mediated virion attachment to host cell
regulation of vasoconstriction
blood vessel diameter maintenance
angiotensin maturation
angiotensin-mediated drinking behavior
viral entry into host cell
tryptophan transport
negative regulation of ERK1 and ERK2 cascade

Displaying entries **1 - 10** of 12 in total

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GO Term
apical plasma membrane
brush border membrane
membrane raft
endoplasmic reticulum lumen
cell surface
extracellular region
extracellular space
plasma membrane
cilium
membrane

Displaying **all 8** entries
GO Term
identical protein binding
endopeptidase activity
virus receptor activity
carboxypeptidase activity
metallocarboxypeptidase activity
metallopeptidase activity
peptidyl-dipeptidase activity
zinc ion binding

Annotation information from UniProt.

Sequence

MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNPGFQNTDDVQTSF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 19 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
43			G87384DY G23729WG	GlyGen
44				GlyGen
53	N-linked (GlcNAc...) asparagine	14754895	G54417MJ G43638QT G79941IJ G12580WI G00912UN G23505EP G83646BJ G44953PJ G08293MJ G56610MH G85740DB G59626AS G54600FO G55382TU G68318VE G83555HU G45504EY G72790NZ G88725PI G10486CT G59937CP G49955PK G72787SB G25987BV G39446WN G35029YA G57776ZU G80475RE G02815KT G57317CE	UniProt GlyGen
90	N-linked (GlcNAc...) asparagine	14754895 15084671 19901337	G32788FZ G01160VV G60967DT G05962QB G30740WO G12341GU G70232NH G37818NZ G69521XL G70888PK G06247RL G35541EV G93718GY G13131HA G49755GI G75568BH G80075MS G57776ZS G85144OK G29545VG G44753VC G54417MJ G68490OW G60834IK G86880BF G27947YN G85282JO G87123QX G79666IR G86752LQ G92135MA G34989PA G43669FQ G88374WZ G07246CJ G10819WX G40926MX G14972EH G12580WI G43223CG G08918WF G00912UN G70441OD G87661QW G83646BJ G08293MJ G27058EU G60033FS G41071NU G85740DB G86182NS G70619PT G59626AS G54600FO G80920RR G65184UU G68318VE G02886BB G83555HU G90659AW G45504EY G62765YT G72790NZ G88725PI G10486CT G59937CP G28541PG G31852PQ G49955PK G72787SB G25987BV G39446WN G35029YA G57776ZU G80475RE G02815KT G57317CE	UniProt GlyGen
103	N-linked (GlcNAc...) asparagine	14754895	G82443XX G32788FZ G56518TU G80669SJ G39471UU G30740WO G12341GU G70232NH G55132BD G69521XL G81124ET G03644CB G06247RL G35541EV G13131HA G49755GI G19517GM G75568BH G80075MS G57776ZS G85144OK G29545VG G44753VC G68490OW G60834IK G86880BF G28622IK G36670VW G90382BL G85282JO G20528HD G87123QX G79666IR G86752LQ G92135MA G95835XS G49284IH G40834TG G43669FQ G07799LX G45395BF G88374WZ G07246CJ G80735OA G14972EH G12580WI G43223CG G58954YZ G37412TK G10846ZT G15038BD G40574BA G08918WF G47737VJ G00912UN G69364JQ G44211QA G70441OD G29651HS G87661QW G83646BJ G44953PJ G76295SF G16175ZV G46691LC G04657PL G25451PN G87051GH G08293MJ G27058EU G83460ZZ G09528DL G56610MH G60033FS G41071NU G85740DB G07755XJ G19379ID G86182NS G19464WF G62792OG G09197ZW G60923RB G70619PT G59626AS G54600FO G01650EU G25079LO G80920RR G67324HN G55382TU G65184UU G42124LM G68318VE G02886BB G83555HU G90659AW G50073PQ G45504EY G03574QJ G37399XV G62765YT G72791KH G72790NZ G88725PI G95177YH G10486CT G05049YU G59937CP G28541PG G15486FH G31852PQ G49955PK G72787SB G25987BV G39446WN G10339FR G41247ZX G35029YA G57776ZU G80475RE G02815KT G82364UA G57317CE G92050GC G20956ZV G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
129			G43417UB	GlyGen
155			G75365RL G94583DZ	GlyGen
257			G93579XB	GlyGen
294			G98896IU	GlyGen
322	N-linked (GlcNAc...) asparagine	14754895	G32926LW G98596OT G19517GM G85144OK G54417MJ G43638QT G41126SR G86752LQ G12580WI G44953PJ G56610MH G85740DB G88725PI G25987BV G80475RE G02815KT	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Attachment and Entry	Homo sapiens
Attachment and Entry	Homo sapiens
Induction of Cell-Cell Fusion	Homo sapiens
Metabolism of Angiotensinogen to Angiotensins	Homo sapiens
Potential therapeutics for SARS	Homo sapiens

Human Protein Atlas

ENSG00000130234

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements