GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 2	24	mild	G58969RU	49
IgM	Patient 2	15	mild	G58969RU	192
IgM	Patient 2	24	mild	G58969RU	234
IgG	Patient 1	6	moderate	G58969RU	25
IgM	Patient 1	6	moderate	G58969RU	48
IgA	Patient 2	3	mild	G58969RU	623
IgG	Patient 2	3	mild	G58969RU	63
IgM	Patient 2	3	mild	G58969RU	309
IgA	Patient 3	-180	mild	G58969RU	264
IgA	Patient 3	11	mild	G58969RU	384
IgG	Patient 3	-180	mild	G58969RU	44
IgM	Patient 3	-180	mild	G58969RU	78
IgA	Patient 3	4	mild	G58969RU	419
IgG	Patient 3	11	mild	G58969RU	45
IgG	Patient 3	4	mild	G58969RU	45
IgM	Patient 3	11	mild	G58969RU	106
IgM	Patient 3	4	mild	G58969RU	105
IgA	Patient 4	12	mild	G58969RU	635
IgG	Patient 4	12	mild	G58969RU	146
IgM	Patient 4	12	mild	G58969RU	1063
IgA	Patient 1	10	moderate	G60761LT	417
IgA	Patient 1	22	moderate	G60761LT	459
IgA	Patient 1	6	moderate	G60761LT	374
IgG	Patient 1	10	moderate	G60761LT	76
IgG	Patient 1	22	moderate	G60761LT	91