GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 2	24	mild	G62826CL	2007
IgM	Patient 2	15	mild	G62826CL	118
IgM	Patient 2	24	mild	G62826CL	98
IgG	Patient 1	6	moderate	G62826CL	25
IgM	Patient 1	6	moderate	G62826CL	35
IgA	Patient 2	3	mild	G62826CL	356
IgG	Patient 2	3	mild	G62826CL	3408
IgM	Patient 2	3	mild	G62826CL	145
IgA	Patient 3	-180	mild	G62826CL	251
IgA	Patient 3	11	mild	G62826CL	367
IgG	Patient 3	-180	mild	G62826CL	47
IgM	Patient 3	-180	mild	G62826CL	78
IgA	Patient 3	4	mild	G62826CL	463
IgG	Patient 3	11	mild	G62826CL	54
IgG	Patient 3	4	mild	G62826CL	61
IgM	Patient 3	11	mild	G62826CL	88
IgM	Patient 3	4	mild	G62826CL	113
IgA	Patient 4	12	mild	G62826CL	416
IgG	Patient 4	12	mild	G62826CL	91
IgM	Patient 4	12	mild	G62826CL	168
IgA	Patient 1	10	moderate	G63074CQ	391
IgA	Patient 1	22	moderate	G63074CQ	353
IgA	Patient 1	6	moderate	G63074CQ	321
IgG	Patient 1	10	moderate	G63074CQ	24
IgG	Patient 1	22	moderate	G63074CQ	24