GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 1	10	moderate	G63074CQ	38
IgM	Patient 1	22	moderate	G63074CQ	56
IgA	Patient 2	15	mild	G63074CQ	397
IgA	Patient 2	24	mild	G63074CQ	514
IgG	Patient 2	15	mild	G63074CQ	39
IgG	Patient 2	24	mild	G63074CQ	46
IgM	Patient 2	15	mild	G63074CQ	162
IgM	Patient 2	24	mild	G63074CQ	266
IgG	Patient 1	6	moderate	G63074CQ	26
IgM	Patient 1	6	moderate	G63074CQ	41
IgA	Patient 2	3	mild	G63074CQ	453
IgG	Patient 2	3	mild	G63074CQ	42
IgM	Patient 2	3	mild	G63074CQ	221
IgA	Patient 3	-180	mild	G63074CQ	269
IgA	Patient 3	11	mild	G63074CQ	391
IgG	Patient 3	-180	mild	G63074CQ	35
IgM	Patient 3	-180	mild	G63074CQ	64
IgA	Patient 3	4	mild	G63074CQ	363
IgG	Patient 3	11	mild	G63074CQ	42
IgG	Patient 3	4	mild	G63074CQ	37
IgM	Patient 3	11	mild	G63074CQ	126
IgM	Patient 3	4	mild	G63074CQ	131
IgA	Patient 4	12	mild	G63074CQ	343
IgG	Patient 4	12	mild	G63074CQ	86
IgM	Patient 4	12	mild	G63074CQ	175