GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G65889KE	121
IgM	Patient 3	-180	mild	G65889KE	130
IgA	Patient 3	4	mild	G65889KE	386
IgG	Patient 3	11	mild	G65889KE	132
IgG	Patient 3	4	mild	G65889KE	77
IgM	Patient 3	11	mild	G65889KE	157
IgM	Patient 3	4	mild	G65889KE	121
IgA	Patient 4	12	mild	G65889KE	412
IgG	Patient 4	12	mild	G65889KE	154
IgM	Patient 4	12	mild	G65889KE	280
IgA	Patient 1	10	moderate	G66937TJ	381
IgA	Patient 1	22	moderate	G66937TJ	368
IgA	Patient 1	6	moderate	G66937TJ	387
IgG	Patient 1	10	moderate	G66937TJ	27
IgG	Patient 1	22	moderate	G66937TJ	34
IgM	Patient 1	10	moderate	G66937TJ	52
IgM	Patient 1	22	moderate	G66937TJ	155
IgA	Patient 2	15	mild	G66937TJ	400
IgA	Patient 2	24	mild	G66937TJ	460
IgG	Patient 2	15	mild	G66937TJ	46
IgG	Patient 2	24	mild	G66937TJ	45
IgM	Patient 2	15	mild	G66937TJ	232
IgM	Patient 2	24	mild	G66937TJ	226
IgG	Patient 1	6	moderate	G66937TJ	30
IgM	Patient 1	6	moderate	G66937TJ	56