GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 2	24	mild	G67045LB	35
IgM	Patient 2	15	mild	G67045LB	127
IgM	Patient 2	24	mild	G67045LB	159
IgG	Patient 1	6	moderate	G67045LB	29
IgM	Patient 1	6	moderate	G67045LB	75
IgA	Patient 2	3	mild	G67045LB	431
IgG	Patient 2	3	mild	G67045LB	43
IgM	Patient 2	3	mild	G67045LB	233
IgA	Patient 3	-180	mild	G67045LB	275
IgA	Patient 3	11	mild	G67045LB	410
IgG	Patient 3	-180	mild	G67045LB	41
IgM	Patient 3	-180	mild	G67045LB	88
IgA	Patient 3	4	mild	G67045LB	458
IgG	Patient 3	11	mild	G67045LB	50
IgG	Patient 3	4	mild	G67045LB	56
IgM	Patient 3	11	mild	G67045LB	231
IgM	Patient 3	4	mild	G67045LB	326
IgA	Patient 4	12	mild	G67045LB	433
IgG	Patient 4	12	mild	G67045LB	77
IgM	Patient 4	12	mild	G67045LB	244
IgA	Patient 1	10	moderate	G68461PT	367
IgA	Patient 1	22	moderate	G68461PT	402
IgA	Patient 1	6	moderate	G68461PT	242
IgG	Patient 1	10	moderate	G68461PT	53
IgG	Patient 1	22	moderate	G68461PT	61