GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 1	10	moderate	G68461PT	32
IgM	Patient 1	22	moderate	G68461PT	64
IgA	Patient 2	15	mild	G68461PT	307
IgA	Patient 2	24	mild	G68461PT	340
IgG	Patient 2	15	mild	G68461PT	164
IgG	Patient 2	24	mild	G68461PT	159
IgM	Patient 2	15	mild	G68461PT	99
IgM	Patient 2	24	mild	G68461PT	107
IgG	Patient 1	6	moderate	G68461PT	41
IgM	Patient 1	6	moderate	G68461PT	32
IgA	Patient 2	3	mild	G68461PT	325
IgG	Patient 2	3	mild	G68461PT	259
IgM	Patient 2	3	mild	G68461PT	91
IgA	Patient 3	-180	mild	G68461PT	2157
IgA	Patient 3	11	mild	G68461PT	2440
IgG	Patient 3	-180	mild	G68461PT	757
IgM	Patient 3	-180	mild	G68461PT	6322
IgA	Patient 3	4	mild	G68461PT	2841
IgG	Patient 3	11	mild	G68461PT	2303
IgG	Patient 3	4	mild	G68461PT	2454
IgM	Patient 3	11	mild	G68461PT	7416
IgM	Patient 3	4	mild	G68461PT	8644
IgA	Patient 4	12	mild	G68461PT	1354
IgG	Patient 4	12	mild	G68461PT	358
IgM	Patient 4	12	mild	G68461PT	1804