GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G68703KI	443
IgA	Patient 1	22	moderate	G68703KI	410
IgA	Patient 1	6	moderate	G68703KI	407
IgG	Patient 1	10	moderate	G68703KI	45
IgG	Patient 1	22	moderate	G68703KI	46
IgM	Patient 1	10	moderate	G68703KI	31
IgM	Patient 1	22	moderate	G68703KI	53
IgA	Patient 2	15	mild	G68703KI	357
IgA	Patient 2	24	mild	G68703KI	391
IgG	Patient 2	15	mild	G68703KI	4110
IgG	Patient 2	24	mild	G68703KI	4116
IgM	Patient 2	15	mild	G68703KI	106
IgM	Patient 2	24	mild	G68703KI	115
IgG	Patient 1	6	moderate	G68703KI	43
IgM	Patient 1	6	moderate	G68703KI	28
IgA	Patient 2	3	mild	G68703KI	389
IgG	Patient 2	3	mild	G68703KI	7132
IgM	Patient 2	3	mild	G68703KI	151
IgA	Patient 3	-180	mild	G68703KI	2658
IgA	Patient 3	11	mild	G68703KI	2748
IgG	Patient 3	-180	mild	G68703KI	3666
IgM	Patient 3	-180	mild	G68703KI	7539
IgA	Patient 3	4	mild	G68703KI	2769
IgG	Patient 3	11	mild	G68703KI	4801
IgG	Patient 3	4	mild	G68703KI	5185