GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G73271MD	47
IgM	Patient 3	-180	mild	G73271MD	80
IgA	Patient 3	4	mild	G73271MD	422
IgG	Patient 3	11	mild	G73271MD	39
IgG	Patient 3	4	mild	G73271MD	38
IgM	Patient 3	11	mild	G73271MD	100
IgM	Patient 3	4	mild	G73271MD	109
IgA	Patient 4	12	mild	G73271MD	427
IgG	Patient 4	12	mild	G73271MD	58
IgM	Patient 4	12	mild	G73271MD	177
IgA	Patient 1	10	moderate	G75896PD	432
IgA	Patient 1	22	moderate	G75896PD	442
IgA	Patient 1	6	moderate	G75896PD	376
IgG	Patient 1	10	moderate	G75896PD	25
IgG	Patient 1	22	moderate	G75896PD	61
IgM	Patient 1	10	moderate	G75896PD	59
IgM	Patient 1	22	moderate	G75896PD	493
IgA	Patient 2	15	mild	G75896PD	890
IgA	Patient 2	24	mild	G75896PD	983
IgG	Patient 2	15	mild	G75896PD	158
IgG	Patient 2	24	mild	G75896PD	153
IgM	Patient 2	15	mild	G75896PD	1475
IgM	Patient 2	24	mild	G75896PD	1420
IgG	Patient 1	6	moderate	G75896PD	25
IgM	Patient 1	6	moderate	G75896PD	52