GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G77974XY	228
IgM	Patient 3	4	mild	G77974XY	230
IgA	Patient 4	12	mild	G77974XY	670
IgG	Patient 4	12	mild	G77974XY	131
IgM	Patient 4	12	mild	G77974XY	970
IgA	Patient 1	10	moderate	G78074HX	374
IgA	Patient 1	22	moderate	G78074HX	341
IgA	Patient 1	6	moderate	G78074HX	342
IgG	Patient 1	10	moderate	G78074HX	27
IgG	Patient 1	22	moderate	G78074HX	33
IgM	Patient 1	10	moderate	G78074HX	46
IgM	Patient 1	22	moderate	G78074HX	69
IgA	Patient 2	15	mild	G78074HX	243
IgA	Patient 2	24	mild	G78074HX	290
IgG	Patient 2	15	mild	G78074HX	44
IgG	Patient 2	24	mild	G78074HX	40
IgM	Patient 2	15	mild	G78074HX	56
IgM	Patient 2	24	mild	G78074HX	60
IgG	Patient 1	6	moderate	G78074HX	28
IgM	Patient 1	6	moderate	G78074HX	41
IgA	Patient 2	3	mild	G78074HX	241
IgG	Patient 2	3	mild	G78074HX	62
IgM	Patient 2	3	mild	G78074HX	87
IgA	Patient 3	-180	mild	G78074HX	259
IgA	Patient 3	11	mild	G78074HX	386