GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 1	10	moderate	G81315DD	90
IgM	Patient 1	22	moderate	G81315DD	364
IgA	Patient 2	15	mild	G81315DD	1098
IgA	Patient 2	24	mild	G81315DD	1393
IgG	Patient 2	15	mild	G81315DD	107
IgG	Patient 2	24	mild	G81315DD	128
IgM	Patient 2	15	mild	G81315DD	785
IgM	Patient 2	24	mild	G81315DD	974
IgG	Patient 1	6	moderate	G81315DD	35
IgM	Patient 1	6	moderate	G81315DD	101
IgA	Patient 2	3	mild	G81315DD	1369
IgG	Patient 2	3	mild	G81315DD	148
IgM	Patient 2	3	mild	G81315DD	1164
IgA	Patient 3	-180	mild	G81315DD	315
IgA	Patient 3	11	mild	G81315DD	541
IgG	Patient 3	-180	mild	G81315DD	55
IgM	Patient 3	-180	mild	G81315DD	182
IgA	Patient 3	4	mild	G81315DD	518
IgG	Patient 3	11	mild	G81315DD	115
IgG	Patient 3	4	mild	G81315DD	90
IgM	Patient 3	11	mild	G81315DD	715
IgM	Patient 3	4	mild	G81315DD	468
IgA	Patient 4	12	mild	G81315DD	5922
IgG	Patient 4	12	mild	G81315DD	4208
IgM	Patient 4	12	mild	G81315DD	11721