GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 1	10	moderate	G82942ZJ	62
IgM	Patient 1	22	moderate	G82942ZJ	300
IgA	Patient 2	15	mild	G82942ZJ	299
IgA	Patient 2	24	mild	G82942ZJ	332
IgG	Patient 2	15	mild	G82942ZJ	27
IgG	Patient 2	24	mild	G82942ZJ	27
IgM	Patient 2	15	mild	G82942ZJ	71
IgG	Patient 1	6	moderate	G82942ZJ	25
IgM	Patient 1	6	moderate	G82942ZJ	48
IgA	Patient 2	3	mild	G82942ZJ	297
IgG	Patient 2	3	mild	G82942ZJ	33
IgM	Patient 2	24	mild	G82942ZJ	74
IgM	Patient 2	3	mild	G82942ZJ	85
IgA	Patient 3	-180	mild	G82942ZJ	261
IgA	Patient 3	11	mild	G82942ZJ	397
IgG	Patient 3	-180	mild	G82942ZJ	39
IgM	Patient 3	-180	mild	G82942ZJ	64
IgA	Patient 3	4	mild	G82942ZJ	381
IgG	Patient 3	11	mild	G82942ZJ	44
IgG	Patient 3	4	mild	G82942ZJ	36
IgM	Patient 3	11	mild	G82942ZJ	116
IgM	Patient 3	4	mild	G82942ZJ	90
IgA	Patient 4	12	mild	G82942ZJ	478
IgG	Patient 4	12	mild	G82942ZJ	86
IgM	Patient 4	12	mild	G82942ZJ	475