GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▼	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G12200GB	21
IgM	Patient 1	10	moderate	G12200GB	31
IgM	Patient 1	22	moderate	G12200GB	41
IgA	Patient 2	15	mild	G12200GB	274
IgA	Patient 2	24	mild	G12200GB	309
IgG	Patient 2	15	mild	G12200GB	297
IgG	Patient 2	24	mild	G12200GB	252
IgM	Patient 2	15	mild	G12200GB	42
IgM	Patient 2	24	mild	G12200GB	43
IgM	Patient 1	6	moderate	G12200GB	29
IgA	Patient 2	3	mild	G12200GB	277
IgG	Patient 2	3	mild	G12200GB	431
IgM	Patient 2	3	mild	G12200GB	44
IgA	Patient 3	-180	mild	G12200GB	2501
IgA	Patient 3	11	mild	G12200GB	2001
IgG	Patient 3	-180	mild	G12200GB	1857
IgG	Patient 3	11	mild	G12200GB	2256
IgM	Patient 3	-180	mild	G12200GB	7415
IgA	Patient 3	4	mild	G12200GB	1965
IgG	Patient 3	4	mild	G12200GB	2024
IgM	Patient 3	11	mild	G12200GB	5944
IgM	Patient 3	4	mild	G12200GB	5741
IgA	Patient 4	12	mild	G12200GB	534
IgG	Patient 4	12	mild	G12200GB	90
IgM	Patient 4	12	mild	G12200GB	465