GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▼	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G11460AB	346
IgA	Patient 1	22	moderate	G11460AB	400
IgA	Patient 1	6	moderate	G11460AB	277
IgG	Patient 1	10	moderate	G11460AB	23
IgG	Patient 1	22	moderate	G11460AB	24
IgG	Patient 1	6	moderate	G11460AB	24
IgM	Patient 1	10	moderate	G11460AB	31
IgM	Patient 1	22	moderate	G11460AB	41
IgA	Patient 2	15	mild	G11460AB	490
IgA	Patient 2	24	mild	G11460AB	630
IgG	Patient 2	15	mild	G11460AB	74
IgG	Patient 2	24	mild	G11460AB	99
IgM	Patient 2	15	mild	G11460AB	626
IgM	Patient 2	24	mild	G11460AB	962
IgM	Patient 1	6	moderate	G11460AB	35
IgA	Patient 2	3	mild	G11460AB	295
IgG	Patient 2	3	mild	G11460AB	42
IgM	Patient 2	3	mild	G11460AB	85
IgA	Patient 3	-180	mild	G11460AB	2380
IgA	Patient 3	11	mild	G11460AB	2789
IgG	Patient 3	-180	mild	G11460AB	832
IgG	Patient 3	11	mild	G11460AB	822
IgM	Patient 3	-180	mild	G11460AB	7129
IgA	Patient 3	4	mild	G11460AB	2698
IgG	Patient 3	4	mild	G11460AB	952