GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 2	3	mild	G86541PE	522
IgM	Patient 2	24	mild	G86541PE	153
IgM	Patient 2	3	mild	G86541PE	215
IgA	Patient 3	-180	mild	G86541PE	246
IgA	Patient 3	11	mild	G86541PE	424
IgG	Patient 3	-180	mild	G86541PE	45
IgM	Patient 3	-180	mild	G86541PE	64
IgA	Patient 3	4	mild	G86541PE	463
IgG	Patient 3	11	mild	G86541PE	180
IgG	Patient 3	4	mild	G86541PE	165
IgM	Patient 3	11	mild	G86541PE	73
IgM	Patient 3	4	mild	G86541PE	69
IgA	Patient 4	12	mild	G86541PE	361
IgG	Patient 4	12	mild	G86541PE	53
IgM	Patient 4	12	mild	G86541PE	96
IgA	Patient 1	10	moderate	G86566MF	372
IgA	Patient 1	22	moderate	G86566MF	334
IgA	Patient 1	6	moderate	G86566MF	360
IgG	Patient 1	10	moderate	G86566MF	23
IgG	Patient 1	22	moderate	G86566MF	22
IgM	Patient 1	10	moderate	G86566MF	37
IgM	Patient 1	22	moderate	G86566MF	41
IgA	Patient 2	15	mild	G86566MF	347
IgA	Patient 2	24	mild	G86566MF	457
IgG	Patient 2	15	mild	G86566MF	36