GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G90223GH	178
IgM	Patient 3	4	mild	G90223GH	214
IgA	Patient 4	12	mild	G90223GH	356
IgG	Patient 4	12	mild	G90223GH	48
IgM	Patient 4	12	mild	G90223GH	125
IgA	Patient 1	10	moderate	G90562PB	388
IgA	Patient 1	22	moderate	G90562PB	394
IgA	Patient 1	6	moderate	G90562PB	336
IgG	Patient 1	10	moderate	G90562PB	2569
IgG	Patient 1	22	moderate	G90562PB	2953
IgM	Patient 1	10	moderate	G90562PB	99
IgM	Patient 1	22	moderate	G90562PB	122
IgA	Patient 2	15	mild	G90562PB	262
IgA	Patient 2	24	mild	G90562PB	296
IgG	Patient 2	15	mild	G90562PB	35
IgG	Patient 2	24	mild	G90562PB	35
IgM	Patient 2	15	mild	G90562PB	67
IgG	Patient 1	6	moderate	G90562PB	2317
IgM	Patient 1	6	moderate	G90562PB	85
IgA	Patient 2	3	mild	G90562PB	285
IgG	Patient 2	3	mild	G90562PB	38
IgM	Patient 2	24	mild	G90562PB	88
IgM	Patient 2	3	mild	G90562PB	82
IgA	Patient 3	-180	mild	G90562PB	314
IgA	Patient 3	11	mild	G90562PB	681