GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 1	10	moderate	G92022ML	90
IgM	Patient 1	22	moderate	G92022ML	277
IgA	Patient 2	15	mild	G92022ML	608
IgA	Patient 2	24	mild	G92022ML	744
IgG	Patient 2	15	mild	G92022ML	120
IgG	Patient 2	24	mild	G92022ML	150
IgM	Patient 2	15	mild	G92022ML	305
IgG	Patient 1	6	moderate	G92022ML	28
IgM	Patient 1	6	moderate	G92022ML	78
IgA	Patient 2	3	mild	G92022ML	745
IgG	Patient 2	3	mild	G92022ML	151
IgM	Patient 2	24	mild	G92022ML	344
IgM	Patient 2	3	mild	G92022ML	436
IgA	Patient 3	-180	mild	G92022ML	320
IgA	Patient 3	11	mild	G92022ML	510
IgG	Patient 3	-180	mild	G92022ML	46
IgM	Patient 3	-180	mild	G92022ML	150
IgA	Patient 3	4	mild	G92022ML	490
IgG	Patient 3	11	mild	G92022ML	73
IgG	Patient 3	4	mild	G92022ML	55
IgM	Patient 3	11	mild	G92022ML	388
IgM	Patient 3	4	mild	G92022ML	252
IgA	Patient 4	12	mild	G92022ML	416
IgG	Patient 4	12	mild	G92022ML	58
IgM	Patient 4	12	mild	G92022ML	165