GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G96865DJ	39871
IgM	Patient 3	4	mild	G96865DJ	42242
IgA	Patient 4	12	mild	G96865DJ	757
IgG	Patient 4	12	mild	G96865DJ	1236
IgM	Patient 4	12	mild	G96865DJ	1216
IgA	Patient 1	10	moderate	G96881BQ	331
IgA	Patient 1	22	moderate	G96881BQ	370
IgA	Patient 1	6	moderate	G96881BQ	316
IgG	Patient 1	10	moderate	G96881BQ	21
IgG	Patient 1	22	moderate	G96881BQ	25
IgM	Patient 1	10	moderate	G96881BQ	30
IgM	Patient 1	22	moderate	G96881BQ	52
IgA	Patient 2	15	mild	G96881BQ	272
IgA	Patient 2	24	mild	G96881BQ	298
IgG	Patient 2	15	mild	G96881BQ	24
IgG	Patient 2	24	mild	G96881BQ	29
IgM	Patient 2	15	mild	G96881BQ	39
IgG	Patient 1	6	moderate	G96881BQ	26
IgM	Patient 1	6	moderate	G96881BQ	27
IgA	Patient 2	3	mild	G96881BQ	272
IgG	Patient 2	3	mild	G96881BQ	26
IgM	Patient 2	24	mild	G96881BQ	51
IgM	Patient 2	3	mild	G96881BQ	45
IgA	Patient 3	-180	mild	G96881BQ	277
IgA	Patient 3	11	mild	G96881BQ	389