GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 2	3	mild	G98068PA	42
IgM	Patient 2	24	mild	G98068PA	133
IgM	Patient 2	3	mild	G98068PA	170
IgA	Patient 3	-180	mild	G98068PA	3647
IgA	Patient 3	11	mild	G98068PA	3067
IgG	Patient 3	-180	mild	G98068PA	2991
IgM	Patient 3	-180	mild	G98068PA	11475
IgA	Patient 3	4	mild	G98068PA	2956
IgG	Patient 3	11	mild	G98068PA	3754
IgG	Patient 3	4	mild	G98068PA	3211
IgM	Patient 3	11	mild	G98068PA	9438
IgM	Patient 3	4	mild	G98068PA	9125
IgA	Patient 4	12	mild	G98068PA	645
IgG	Patient 4	12	mild	G98068PA	150
IgM	Patient 4	12	mild	G98068PA	1027
IgA	Patient 1	10	moderate	G98240FC	383
IgA	Patient 1	22	moderate	G98240FC	422
IgA	Patient 1	6	moderate	G98240FC	344
IgG	Patient 1	10	moderate	G98240FC	39
IgG	Patient 1	22	moderate	G98240FC	58
IgM	Patient 1	10	moderate	G98240FC	72
IgM	Patient 1	22	moderate	G98240FC	263
IgA	Patient 2	15	mild	G98240FC	424
IgA	Patient 2	24	mild	G98240FC	441
IgG	Patient 2	15	mild	G98240FC	344