GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G08520NM	24
IgM	Patient 1	10	moderate	G08520NM	46
IgM	Patient 1	22	moderate	G08520NM	221
IgA	Patient 2	15	mild	G08520NM	381
IgA	Patient 2	24	mild	G08520NM	437
IgG	Patient 2	15	mild	G08520NM	36
IgG	Patient 2	24	mild	G08520NM	37
IgM	Patient 2	15	mild	G08520NM	177
IgM	Patient 2	24	mild	G08520NM	179
IgM	Patient 1	6	moderate	G08520NM	45
IgA	Patient 2	3	mild	G08520NM	432
IgG	Patient 2	3	mild	G08520NM	43
IgM	Patient 2	3	mild	G08520NM	235
IgA	Patient 3	-180	mild	G08520NM	257
IgA	Patient 3	11	mild	G08520NM	432
IgG	Patient 3	-180	mild	G08520NM	58
IgG	Patient 3	11	mild	G08520NM	35
IgM	Patient 3	-180	mild	G08520NM	105
IgA	Patient 3	4	mild	G08520NM	461
IgG	Patient 3	4	mild	G08520NM	38
IgM	Patient 3	11	mild	G08520NM	80
IgM	Patient 3	4	mild	G08520NM	94
IgA	Patient 4	12	mild	G08520NM	507
IgG	Patient 4	12	mild	G08520NM	76
IgM	Patient 4	12	mild	G08520NM	410