GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G09482NW	423
IgA	Patient 1	22	moderate	G09482NW	381
IgA	Patient 1	6	moderate	G09482NW	387
IgG	Patient 1	10	moderate	G09482NW	33
IgG	Patient 1	22	moderate	G09482NW	45
IgG	Patient 1	6	moderate	G09482NW	34
IgM	Patient 1	10	moderate	G09482NW	115
IgM	Patient 1	22	moderate	G09482NW	326
IgA	Patient 2	15	mild	G09482NW	389
IgA	Patient 2	24	mild	G09482NW	464
IgG	Patient 2	15	mild	G09482NW	49
IgG	Patient 2	24	mild	G09482NW	46
IgM	Patient 2	15	mild	G09482NW	259
IgM	Patient 2	24	mild	G09482NW	298
IgM	Patient 1	6	moderate	G09482NW	150
IgA	Patient 2	3	mild	G09482NW	455
IgG	Patient 2	3	mild	G09482NW	54
IgM	Patient 2	3	mild	G09482NW	356
IgA	Patient 3	-180	mild	G09482NW	211
IgA	Patient 3	11	mild	G09482NW	771
IgG	Patient 3	-180	mild	G09482NW	49
IgG	Patient 3	11	mild	G09482NW	132
IgM	Patient 3	-180	mild	G09482NW	99
IgA	Patient 3	4	mild	G09482NW	750
IgG	Patient 3	4	mild	G09482NW	137