GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G09482NW	1248
IgM	Patient 3	4	mild	G09482NW	1232
IgA	Patient 4	12	mild	G09482NW	823
IgG	Patient 4	12	mild	G09482NW	157
IgM	Patient 4	12	mild	G09482NW	1495
IgA	Patient 1	10	moderate	G09609EN	331
IgA	Patient 1	22	moderate	G09609EN	404
IgA	Patient 1	6	moderate	G09609EN	331
IgG	Patient 1	10	moderate	G09609EN	25
IgG	Patient 1	22	moderate	G09609EN	42
IgG	Patient 1	6	moderate	G09609EN	27
IgM	Patient 1	10	moderate	G09609EN	50
IgM	Patient 1	22	moderate	G09609EN	239
IgA	Patient 2	15	mild	G09609EN	717
IgA	Patient 2	24	mild	G09609EN	911
IgG	Patient 2	15	mild	G09609EN	91
IgG	Patient 2	24	mild	G09609EN	107
IgM	Patient 2	15	mild	G09609EN	341
IgM	Patient 2	24	mild	G09609EN	425
IgM	Patient 1	6	moderate	G09609EN	52
IgA	Patient 2	3	mild	G09609EN	986
IgG	Patient 2	3	mild	G09609EN	127
IgM	Patient 2	3	mild	G09609EN	547
IgA	Patient 3	-180	mild	G09609EN	250
IgA	Patient 3	11	mild	G09609EN	422