GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G15209MJ	25
IgM	Patient 1	10	moderate	G15209MJ	35
IgM	Patient 1	22	moderate	G15209MJ	114
IgA	Patient 2	15	mild	G15209MJ	430
IgA	Patient 2	24	mild	G15209MJ	461
IgG	Patient 2	15	mild	G15209MJ	459
IgG	Patient 2	24	mild	G15209MJ	439
IgM	Patient 2	15	mild	G15209MJ	193
IgM	Patient 2	24	mild	G15209MJ	197
IgM	Patient 1	6	moderate	G15209MJ	39
IgA	Patient 2	3	mild	G15209MJ	462
IgG	Patient 2	3	mild	G15209MJ	687
IgM	Patient 2	3	mild	G15209MJ	272
IgA	Patient 3	-180	mild	G15209MJ	253
IgA	Patient 3	11	mild	G15209MJ	372
IgG	Patient 3	-180	mild	G15209MJ	44
IgG	Patient 3	11	mild	G15209MJ	570
IgM	Patient 3	-180	mild	G15209MJ	52
IgA	Patient 3	4	mild	G15209MJ	418
IgG	Patient 3	4	mild	G15209MJ	547
IgM	Patient 3	11	mild	G15209MJ	85
IgM	Patient 3	4	mild	G15209MJ	87
IgA	Patient 4	12	mild	G15209MJ	360
IgG	Patient 4	12	mild	G15209MJ	54
IgM	Patient 4	12	mild	G15209MJ	105