GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G21290RB	45
IgM	Patient 1	10	moderate	G21290RB	129
IgM	Patient 1	22	moderate	G21290RB	185
IgA	Patient 2	15	mild	G21290RB	434
IgA	Patient 2	24	mild	G21290RB	518
IgG	Patient 2	15	mild	G21290RB	1278
IgG	Patient 2	24	mild	G21290RB	1256
IgM	Patient 2	15	mild	G21290RB	296
IgM	Patient 2	24	mild	G21290RB	363
IgM	Patient 1	6	moderate	G21290RB	87
IgA	Patient 2	3	mild	G21290RB	535
IgG	Patient 2	3	mild	G21290RB	1432
IgM	Patient 2	3	mild	G21290RB	449
IgA	Patient 3	-180	mild	G21290RB	337
IgA	Patient 3	11	mild	G21290RB	499
IgG	Patient 3	-180	mild	G21290RB	57
IgM	Patient 3	-180	mild	G21290RB	198
IgA	Patient 3	4	mild	G21290RB	525
IgG	Patient 3	11	mild	G21290RB	74
IgG	Patient 3	4	mild	G21290RB	73
IgM	Patient 3	11	mild	G21290RB	305
IgM	Patient 3	4	mild	G21290RB	316
IgA	Patient 4	12	mild	G21290RB	518
IgG	Patient 4	12	mild	G21290RB	100
IgM	Patient 4	12	mild	G21290RB	487