GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G21320TF	393
IgA	Patient 1	22	moderate	G21320TF	394
IgA	Patient 1	6	moderate	G21320TF	286
IgG	Patient 1	10	moderate	G21320TF	23
IgG	Patient 1	22	moderate	G21320TF	33
IgG	Patient 1	6	moderate	G21320TF	24
IgM	Patient 1	10	moderate	G21320TF	42
IgM	Patient 1	22	moderate	G21320TF	152
IgA	Patient 2	15	mild	G21320TF	284
IgA	Patient 2	24	mild	G21320TF	318
IgG	Patient 2	15	mild	G21320TF	249
IgG	Patient 2	24	mild	G21320TF	205
IgM	Patient 2	15	mild	G21320TF	73
IgM	Patient 2	24	mild	G21320TF	78
IgM	Patient 1	6	moderate	G21320TF	38
IgA	Patient 2	3	mild	G21320TF	313
IgG	Patient 2	3	mild	G21320TF	446
IgM	Patient 2	3	mild	G21320TF	102
IgA	Patient 3	-180	mild	G21320TF	239
IgA	Patient 3	11	mild	G21320TF	425
IgG	Patient 3	-180	mild	G21320TF	36
IgM	Patient 3	-180	mild	G21320TF	64
IgA	Patient 3	4	mild	G21320TF	458
IgG	Patient 3	11	mild	G21320TF	42
IgG	Patient 3	4	mild	G21320TF	48