GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G21320TF	81
IgM	Patient 3	4	mild	G21320TF	104
IgA	Patient 4	12	mild	G21320TF	402
IgG	Patient 4	12	mild	G21320TF	55
IgM	Patient 4	12	mild	G21320TF	100
IgA	Patient 1	10	moderate	G21460SG	346
IgA	Patient 1	22	moderate	G21460SG	412
IgA	Patient 1	6	moderate	G21460SG	342
IgG	Patient 1	10	moderate	G21460SG	26
IgG	Patient 1	22	moderate	G21460SG	30
IgG	Patient 1	6	moderate	G21460SG	25
IgM	Patient 1	10	moderate	G21460SG	44
IgM	Patient 1	22	moderate	G21460SG	104
IgA	Patient 2	15	mild	G21460SG	358
IgA	Patient 2	24	mild	G21460SG	380
IgG	Patient 2	15	mild	G21460SG	345
IgG	Patient 2	24	mild	G21460SG	284
IgM	Patient 2	15	mild	G21460SG	155
IgM	Patient 2	24	mild	G21460SG	153
IgM	Patient 1	6	moderate	G21460SG	41
IgA	Patient 2	3	mild	G21460SG	405
IgG	Patient 2	3	mild	G21460SG	607
IgM	Patient 2	3	mild	G21460SG	242
IgA	Patient 3	-180	mild	G21460SG	255
IgA	Patient 3	11	mild	G21460SG	451