GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G24617OK	399
IgA	Patient 1	22	moderate	G24617OK	408
IgA	Patient 1	6	moderate	G24617OK	337
IgG	Patient 1	10	moderate	G24617OK	24
IgG	Patient 1	22	moderate	G24617OK	31
IgG	Patient 1	6	moderate	G24617OK	26
IgM	Patient 1	10	moderate	G24617OK	55
IgM	Patient 1	22	moderate	G24617OK	143
IgA	Patient 2	15	mild	G24617OK	424
IgA	Patient 2	24	mild	G24617OK	519
IgG	Patient 2	15	mild	G24617OK	71
IgG	Patient 2	24	mild	G24617OK	69
IgM	Patient 2	15	mild	G24617OK	124
IgM	Patient 2	24	mild	G24617OK	156
IgM	Patient 1	6	moderate	G24617OK	43
IgA	Patient 2	3	mild	G24617OK	492
IgG	Patient 2	3	mild	G24617OK	78
IgM	Patient 2	3	mild	G24617OK	174
IgA	Patient 3	-180	mild	G24617OK	3775
IgA	Patient 3	11	mild	G24617OK	3123
IgG	Patient 3	-180	mild	G24617OK	2836
IgM	Patient 3	-180	mild	G24617OK	11712
IgA	Patient 3	4	mild	G24617OK	3765
IgG	Patient 3	11	mild	G24617OK	2427
IgG	Patient 3	4	mild	G24617OK	2856