GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G25473LQ	469
IgG	Patient 2	3	mild	G25473LQ	43
IgM	Patient 2	3	mild	G25473LQ	247
IgA	Patient 3	-180	mild	G25473LQ	275
IgA	Patient 3	11	mild	G25473LQ	400
IgG	Patient 3	-180	mild	G25473LQ	37
IgM	Patient 3	-180	mild	G25473LQ	72
IgA	Patient 3	4	mild	G25473LQ	416
IgG	Patient 3	11	mild	G25473LQ	48
IgG	Patient 3	4	mild	G25473LQ	44
IgM	Patient 3	11	mild	G25473LQ	133
IgM	Patient 3	4	mild	G25473LQ	144
IgA	Patient 4	12	mild	G25473LQ	332
IgG	Patient 4	12	mild	G25473LQ	107
IgM	Patient 4	12	mild	G25473LQ	201
IgA	Patient 1	10	moderate	G25559RS	612
IgA	Patient 1	22	moderate	G25559RS	630
IgA	Patient 1	6	moderate	G25559RS	686
IgG	Patient 1	10	moderate	G25559RS	268
IgG	Patient 1	22	moderate	G25559RS	329
IgG	Patient 1	6	moderate	G25559RS	328
IgM	Patient 1	10	moderate	G25559RS	61
IgM	Patient 1	22	moderate	G25559RS	67
IgA	Patient 2	15	mild	G25559RS	1802
IgA	Patient 2	24	mild	G25559RS	2725