GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G26295XE	5294
IgM	Patient 3	4	mild	G26295XE	4981
IgA	Patient 4	12	mild	G26295XE	406
IgG	Patient 4	12	mild	G26295XE	115
IgM	Patient 4	12	mild	G26295XE	116
IgA	Patient 1	10	moderate	G27689OB	434
IgA	Patient 1	22	moderate	G27689OB	419
IgA	Patient 1	6	moderate	G27689OB	446
IgG	Patient 1	10	moderate	G27689OB	27
IgG	Patient 1	22	moderate	G27689OB	35
IgG	Patient 1	6	moderate	G27689OB	26
IgM	Patient 1	10	moderate	G27689OB	53
IgM	Patient 1	22	moderate	G27689OB	170
IgA	Patient 2	15	mild	G27689OB	441
IgA	Patient 2	24	mild	G27689OB	470
IgG	Patient 2	15	mild	G27689OB	1342
IgG	Patient 2	24	mild	G27689OB	1153
IgM	Patient 2	15	mild	G27689OB	222
IgM	Patient 2	24	mild	G27689OB	224
IgM	Patient 1	6	moderate	G27689OB	53
IgA	Patient 2	3	mild	G27689OB	470
IgG	Patient 2	3	mild	G27689OB	2008
IgM	Patient 2	3	mild	G27689OB	304
IgA	Patient 3	-180	mild	G27689OB	251
IgA	Patient 3	11	mild	G27689OB	412