GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G00054MO	23
IgM	Patient 1	10	moderate	G00054MO	33
IgM	Patient 1	22	moderate	G00054MO	29
IgA	Patient 2	15	mild	G00054MO	219
IgA	Patient 2	24	mild	G00054MO	243
IgG	Patient 2	15	mild	G00054MO	35
IgG	Patient 2	24	mild	G00054MO	23
IgM	Patient 2	15	mild	G00054MO	45
IgM	Patient 2	24	mild	G00054MO	39
IgM	Patient 1	6	moderate	G00054MO	25
IgA	Patient 2	3	mild	G00054MO	222
IgG	Patient 2	3	mild	G00054MO	24
IgM	Patient 2	3	mild	G00054MO	35
IgA	Patient 3	-180	mild	G00054MO	238
IgA	Patient 3	11	mild	G00054MO	410
IgG	Patient 3	-180	mild	G00054MO	44
IgG	Patient 3	11	mild	G00054MO	46
IgM	Patient 3	-180	mild	G00054MO	75
IgA	Patient 3	4	mild	G00054MO	364
IgG	Patient 3	4	mild	G00054MO	41
IgM	Patient 3	11	mild	G00054MO	91
IgM	Patient 3	4	mild	G00054MO	81
IgA	Patient 4	12	mild	G00054MO	427
IgG	Patient 4	12	mild	G00054MO	85
IgM	Patient 4	12	mild	G00054MO	137