GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G29857RC	23
IgM	Patient 1	10	moderate	G29857RC	34
IgM	Patient 1	22	moderate	G29857RC	85
IgA	Patient 2	15	mild	G29857RC	414
IgA	Patient 2	24	mild	G29857RC	510
IgG	Patient 2	15	mild	G29857RC	37
IgG	Patient 2	24	mild	G29857RC	41
IgM	Patient 2	15	mild	G29857RC	175
IgM	Patient 2	24	mild	G29857RC	221
IgM	Patient 1	6	moderate	G29857RC	34
IgA	Patient 2	3	mild	G29857RC	510
IgG	Patient 2	3	mild	G29857RC	46
IgM	Patient 2	3	mild	G29857RC	270
IgA	Patient 3	-180	mild	G29857RC	274
IgA	Patient 3	11	mild	G29857RC	438
IgG	Patient 3	-180	mild	G29857RC	52
IgM	Patient 3	-180	mild	G29857RC	95
IgA	Patient 3	4	mild	G29857RC	474
IgG	Patient 3	11	mild	G29857RC	32
IgG	Patient 3	4	mild	G29857RC	36
IgM	Patient 3	11	mild	G29857RC	76
IgM	Patient 3	4	mild	G29857RC	88
IgA	Patient 4	12	mild	G29857RC	349
IgG	Patient 4	12	mild	G29857RC	80
IgM	Patient 4	12	mild	G29857RC	164