GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G31265MS	40
IgM	Patient 3	-180	mild	G31265MS	70
IgA	Patient 3	4	mild	G31265MS	455
IgG	Patient 3	11	mild	G31265MS	56
IgG	Patient 3	4	mild	G31265MS	50
IgM	Patient 3	11	mild	G31265MS	104
IgM	Patient 3	4	mild	G31265MS	103
IgA	Patient 4	12	mild	G31265MS	359
IgG	Patient 4	12	mild	G31265MS	54
IgM	Patient 4	12	mild	G31265MS	109
IgA	Patient 1	10	moderate	G32473MI	327
IgA	Patient 1	22	moderate	G32473MI	403
IgA	Patient 1	6	moderate	G32473MI	334
IgG	Patient 1	10	moderate	G32473MI	45
IgG	Patient 1	22	moderate	G32473MI	55
IgG	Patient 1	6	moderate	G32473MI	42
IgM	Patient 1	10	moderate	G32473MI	45
IgM	Patient 1	22	moderate	G32473MI	142
IgA	Patient 2	15	mild	G32473MI	403
IgA	Patient 2	24	mild	G32473MI	473
IgG	Patient 2	15	mild	G32473MI	6271
IgG	Patient 2	24	mild	G32473MI	6518
IgM	Patient 2	15	mild	G32473MI	184
IgM	Patient 2	24	mild	G32473MI	221
IgM	Patient 1	6	moderate	G32473MI	38