GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G35446HX	886
IgM	Patient 3	4	mild	G35446HX	1747
IgA	Patient 4	12	mild	G35446HX	1038
IgG	Patient 4	12	mild	G35446HX	259
IgM	Patient 4	12	mild	G35446HX	2083
IgA	Patient 1	10	moderate	G36191CD	253
IgA	Patient 1	22	moderate	G36191CD	269
IgA	Patient 1	6	moderate	G36191CD	278
IgG	Patient 1	10	moderate	G36191CD	24
IgG	Patient 1	22	moderate	G36191CD	31
IgM	Patient 1	10	moderate	G36191CD	35
IgM	Patient 1	22	moderate	G36191CD	89
IgA	Patient 2	15	mild	G36191CD	386
IgA	Patient 2	24	mild	G36191CD	444
IgG	Patient 2	15	mild	G36191CD	47
IgG	Patient 2	24	mild	G36191CD	56
IgM	Patient 2	15	mild	G36191CD	208
IgM	Patient 2	24	mild	G36191CD	241
IgG	Patient 1	6	moderate	G36191CD	26
IgM	Patient 1	6	moderate	G36191CD	35
IgA	Patient 2	3	mild	G36191CD	530
IgG	Patient 2	3	mild	G36191CD	80
IgM	Patient 2	3	mild	G36191CD	389
IgA	Patient 3	-180	mild	G36191CD	289
IgA	Patient 3	11	mild	G36191CD	346